Publication: 4366

Publication: 4366

ACS10, a cytarabine pharmacogenomics score impacts survival in pediatric and adolescent and young adult patients with AML, and associates with outcome differences in Black patients (Alliance).

PubMed

PMC

QxMD

DOI

Google Scholar

Citation:: JAMA Netw Open vol 8 (6) e2516296

Year:: 2025
Type:: Manuscript
Funding:: NCTN
Endpoint:: Secondary-not-in-original
Analysis:: Primary
Data Sharing:: Alliance-data-source,-internal-user
Status:: Presented/Published
Citation Status:: epub-ppub

Note:

Methodological:: No
Biospecimen:: Yes
SDC:: No
Book Volume:

Parents:: 4130
Children:: None

Program:: OGC
Primary Committee:: Leukemia
Sec. Committees:

Pharmas:
Grants:: U10CA180821, U10CA180882, U24CA196171, UG1CA189850, UG1CA189824, UG1CA233247, UG1CA233253, UG1CA233327, UG1CA233328, UG1CA233331, UG1CA233339, R01-CA132946, AGR DTD 04-26-2018, R01-CA-262496, R01-CA-284595-01, R01-CA-283574-01, R01-LM-013879, T32HG008958

Corr. Author:
Authors:: Richard J. Marrero Vivek M. Shastri Deedra Nicolet Krzysztof Mrózek Christopher J. Walker William G. Blum Bayard L. Powell Jonathan E. Kolitz Joseph O. Moore Geoffrey L. Uy Wendy Stock Andrew J. Carroll John C. Byrd Richard Aplenc Todd M. Cooper Alan S. Gamis Stanley Pounds Jim Wang Todd A. Alonzo Soheil Meschinchi Ann-Kathrin Eisfeld Edward A. Kolb Jatinder K. Lamba

Networks:: CT063, LAPS-AL002, LAPS-IL057, LAPS-MO011, LAPS-NC010, LAPS-OH007, LAPS-PA015, NC002, NORTHWELL

Study: Alliance-A152424
Multiple Studies, or Legacy Studies in Alliance Study:: CALGB-20202, Alliance-A152424, CALGB-8461, CALGB-9665
Phases:: N/A, N/A

Keywords:: leukemia, AML, cytarabine, drug resistance, pharmacogenomics, SNP